咨詢：  （重慶） （貴陽(yáng)）

Anti-MT-ATP6 antibody (ab102573)抗線粒體MT-ATP6抗體產(chǎn)品信息：

• Product nameAnti-MT-ATP6 antibodySee all MT-ATP6 primary antibodies ...
• Description

  Rabbit polyclonal to MT-ATP6

• Tested applicationsICC/IF, WB more details
• Species reactivity

  Reacts with: Human

• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human MT-ATP6.

  Read Abcam's proprietary immunogen policy

   

   

• Positive control
  • This antibody gave a positive signal in Human Skin tissue lysate.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7.40
  Preservative: 0.02% Sodium azide
  Constituent: PBS
  Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.

• Concentration 200 µl at 0.1 mg/ml

• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab102573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

• FunctionMitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
• Involvement in diseaseDefects in MT-ATP6 are the cause of neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP) [MIM:551500].
  Defects in MT-ATP6 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.
  Defects in MT-ATP6 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
  Defects in MT-ATP6 are a cause of mitochondrial infantile bilateral striatal necrosis (MIBSN) [MIM:500003]. Bilateral striatal necrosis is a neurological disorder resembling Leigh syndrome.
• Sequence similaritiesBelongs to the ATPase A chain family.
• Cellular localizationMitochondrion inner membrane.
• Information by UniProt

• Database links

  • Entrez Gene: 4508 Human
  • SwissProt: P00846 Human

• Alternative names

  • ATP synthase subunit a antibody
  • ATP6 antibody
  • ATP6_HUMAN antibody

  see all

Anti-MT-ATP6 antibody images

• 

  Western blot - Anti-MT-ATP6 antibody (ab102573)

  Anti-MT-ATP6 antibody (ab102573) at 1/250 dilution + Skin (Human) Tissue Lysate - adult normal tissue (ab30166) at 10 µg
  
  Secondary
  Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
  developed using the ECL technique
  
  Performed under reducing conditions.
  
  Predicted band size : 25 kDa
  Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  Additional bands at : 46 kDa. We are unsure as to the identity of these extra bands.
  
  Exposure time : 20 minutes

• 

  Immunocytochemistry/ Immunofluorescence - Anti-MT-ATP6 antibody (ab102573)

  ICC/IF image of ab102573 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab102573 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

公司介紹：

    Abcam位于英國(guó)的劍橋科學(xué)園，成立于1998年，專門生產(chǎn)和分銷研究型抗體。主要?jiǎng)?chuàng)立人Jonathan Milner和實(shí)驗(yàn)室同事構(gòu)思成立一間了解科研人員需要的網(wǎng)上抗體公司，理念是Abcam銷售質(zhì)量高的抗體，并提供zui全面、誠(chéng)實(shí)、時(shí)新的說(shuō)明書，快速的送貨服務(wù)，及高效率的顧客和服務(wù)。我們的在線目錄(www.bcs2008.com) 已有差不多100,000種抗體和試劑，并不斷添加，供應(yīng)予百多個(gè)國(guó)家。Abcam于2005年11月在倫敦證券交易所上市，在美國(guó)馬薩諸塞州、日本東京及香港均設(shè)有分公司。

    Abcam 一直致力加強(qiáng)產(chǎn)品線，為使研究員更容易找到蛋白質(zhì)研究試劑產(chǎn)品，在2011并購(gòu)了美國(guó)的MitoSciences公司，加強(qiáng)了免疫分析方面的產(chǎn)品供應(yīng)；同年也并購(gòu)了英國(guó)的Ascent Scientific 公司，開展了生化試劑的供應(yīng)。在2012年，Abcam并購(gòu)了美國(guó)的Epitomics 公司，成為一家有的RabMAbs® 供應(yīng)商。

    Abcam 的 目標(biāo)是給世界上的抗體建立zui大的在線目錄，為各地科學(xué)家提供*產(chǎn)品，成為各國(guó)科學(xué)界的重要伙伴。我們?yōu)樗挟a(chǎn)品提供來(lái)使客戶獲得預(yù)期的結(jié) 果。為提供高質(zhì)量的抗體來(lái)指向盡可能多的靶蛋白，我們盡所能在盡可能多的應(yīng)用和物種中檢測(cè)每種抗體。我們相信誠(chéng)信才是上策，在我們的上會(huì)發(fā)布有關(guān)我們 每一種產(chǎn)品的盡可能多的信息。

更多產(chǎn)品：

Abcamab1132Mouse monoclonal [1718] to Thyroid Hormone Receptor100ul3996Thyroid Hormone Receptor抗體一抗

Abcamab11320Rabbit polyclonal to gamma Tubulin - Centrosome Marker100ul3996gamma Tubulin抗體一抗

Abcamab11321Rabbit polyclonal to gamma Tubulin - Centrosome Marker100ul3996gamma Tubulin抗體一抗

Abcamab11322Mouse monoclonal [TUB-11] to epsilon Tubulin100ul3996epsilon Tubulin抗體一抗

Abcamab11323Mouse monoclonal [6-11B-1] to Tubulin （acetyl K40）100ul3996Tubulin抗體一抗

Abcamab11324Mouse monoclonal [B3] to Tubulin - Polyglutamylated100ul4274Tubulin抗體一抗

Abcamab11325Mouse monoclonal [TUB-1A2] to Tubulin100ul3996Tubulin抗體一抗

Abcamab11326Mouse monoclonal [100/2] to alpha Adaptin100ul3996alpha Adaptin抗體一抗

Abcamab11327Mouse monoclonal [100/1] to AP1+2 beta1 00ul3996beta 1/2 Adaptin抗體一抗

Abcamab11328Mouse monoclonal [100/3] to gamma Adaptin100ul3996gamma Adaptin抗體一抗

Abcamab11329Mouse monoclonal [AP180-I] to AP180100ul3996AP18抗體一抗

Abcam  ab12370Mouse monoclonal [3D10] to Syntaxin 6100ug3996Syntaxin 6hystemcell一抗

Abcam  ab1238Goat polyclonal to DDDDK tag （HRP）200ug3996DDDDK taghystemcell一抗

Abcam  ab12380CPEB3 peptide100ug3286CPEB3蛋白/多肽多肽

Abcam  ab12385Rabbit polyclonal to BDNF （Biotin）25ug3996BDNFhystemcell一抗

Abcam  ab12389SUZ12 peptide100ug2010SUZ12蛋白/多肽多肽

Abcam  ab1239Mouse monoclonal [FS02+733] to CD38+CD8 （Dual color: FITC+PE）500ul3996CD38/CD8hystemcell一抗

Abcam  ab12392PSD93 peptide100ug2010PSD93蛋白/多肽多肽

Abcam  ab12394APH1a peptide100ug2010APH1a蛋白/多肽多肽

Abcam  ab12397Pin1 peptide100ug2010Pin1蛋白/多肽多肽

Abcam  ab12399Glutamate Receptor 1 （AMPA subtype） peptide - phospho T840100ug2010Glutamate Receptor 1 （AMPA subtype）蛋白/多肽多肽

Abcam  ab1240Goat polyclonal to DDDDK tag （Agarose）100ug3996DDDDK taghystemcell一抗

Abcam  ab12400Rabbit polyclonal to STAT650ug3996STAT6hystemcell一抗

Abcam  ab12401Rabbit polyclonal to STAT650ul3996STAT6hystemcell一抗

Abcam  ab12402p40 peptide100ug2010p40蛋白/多肽多肽

Abcam  ab12403Rabbit polyclonal to STAT6 （phospho Y641）25ul3996STAT6hystemcell一抗

Abcam  ab12404Twilight peptide100ug2010Twilight蛋白/多肽多肽

Abcam  ab12405Mouse monoclonal [44.1] to KMT1A/SUV39H1 - ChIP Grade50ul3885SUV39H1hystemcell一抗

Abcam  ab12407Mouse monoclonal [Mab1] to Topoisomerase I50ul3996Topoisomerase Ihystemcell一抗

Abcam  ab12408Geminin peptide100ug2010Geminin蛋白/多肽多肽

Abcam  ab12409Rabbit polyclonal to PPAR gamma 2 50ul3996PPAR gamma 2hystemcell一抗

Abcam  ab1241Mouse monoclonal [L1C1+CB19] to Kappa+CD19 （Dual color: FITC+PE）500ul3996Kappa/CD19hystemcell一抗

Abcam  ab12411YB1 peptide100ug2010YB1蛋白/多肽多肽

Abcam  ab12414Rabbit polyclonal to cAMP100tests3996cAMPhystemcell一抗

Abcam  ab12416Rabbit polyclonal to cGMP100tests3996cGMPhystemcell一抗

Abcam  ab12417SAP102 peptide100ug2010SAP102蛋白/多肽多肽

Abcam  ab12419PSD95 peptide100ug2010PSD95蛋白/多肽多肽

Abcam  ab1242Mouse monoclonal [GA170+CB19] to Lambda+CD19 （Dual color: FITC+PE）500ul3996Lambda/CD19hystemcell一抗

Abcam  ab12421Mouse monoclonal [CYT2-21] to Cytohesin 250ul3996Cytohesin 2hystemcell一抗

Abcam  ab12423Rabbit polyclonal to ASAP1/DDEF150ul3996ASAP1/DDEF1hystemcell一抗

Abcam  ab12425Mouse monoclonal [CYT1-82] to Cytohesin 150ul3996Cytohesin 1hystemcell一抗

Abcam  ab12427Rabbit polyclonal to D4 GDI50ug3996D4 GDIhystemcell一抗

Abcam  ab1243Mouse monoclonal [GA110] to CD2500ul3996CD2hystemcell一抗

Abcam  ab12432Rabbit polyclonal to Farnesyl50ul3996Farnesylhystemcell一抗

Abcam  ab12434Glutamate Receptor 1 （AMPA subtype） peptide - unmodified100ug2010Glutamate Receptor 1 （AMPA subtype）蛋白/多肽多肽

Abcam  ab12437p95 NBS1 peptide - unmodified100ug2010p95 NBS1蛋白/多肽多肽

Abcam  ab12446Mouse monoclonal [8F12 ] to Chk2100ug3996Chk2hystemcell一抗

Abcam  ab12447Mouse monoclonal [5H9] to RAD52100ug3996RAD52hystemcell一抗

Abcam  ab12448Mouse monoclonal [13E4] to Rad51100ug3996Rad51hystemcell一抗

Abcam  ab12449Mouse monoclonal [339 ] to PCNA - Proliferation Marker100ug3996PCNAhystemcell一抗

Abcam  ab1245Mouse monoclonal [BB12] to CD3 （Phycoerythrin）500ul3996CD3hystemcell一抗

Abcam  ab12450Mouse monoclonal [103 ] to FANCD2100ug3996FANCD2hystemcell一抗

Abcam  ab12454Mouse monoclonal [4D9] to Engrailed and Invected200ug3885Engrailed and Invectedhystemcell一抗

Abcam  ab12455Mouse monoclonal [BP102] to Axons of the Drosophila CNS100ug3996Axons of the Drosophila CNShystemcell一抗

Abcam  ab12457Caspase 1 siRNA vector20ug8103Caspase 1 siRNA vector 試劑盒及其他產(chǎn)品載體

Abcam  ab1246Mouse monoclonal [EDU-2] to CD4500ul3996CD4hystemcell一抗

Abcam  ab1247Mouse monoclonal [BB12] to CD3500ul3996CD3hystemcell一抗

Abcam  ab12471Goat polyclonal to FGF1650ug3996FGF16hystemcell一抗

Abcam  ab1248Mouse monoclonal [CRIS1] to CD5500ul3996CD5hystemcell一抗

Abcam  ab1249Mouse monoclonal [Huly-m2] to CD7500ul3996CD7hystemcell一抗

Abcam  ab12490Caspase 3 siRNA vector20ug8103Caspase 3 siRNA vector試劑盒及其他產(chǎn)品載體

Abcam  ab12496Caspase 8 siRNA vector20ug8103Caspase 8 siRNA vector試劑盒及其他產(chǎn)品載體

Abcam  ab12498Rabbit polyclonal to AMACR500ul3996AMACRhystemcell一抗

Abcam  ab1250Mouse monoclonal [733] to CD8500ul3996CD8hystemcell一抗

Abcam  ab12501Mouse monoclonal [MUM1p] to MUM1500ul3996MUM1hystemcell一抗

Abcam  ab12502Mouse monoclonal [PNL2] to Melanoma250ul3996Melanomahystemcell一抗

Abcam  ab12504Caspase 9 siRNA vector20ug8103Caspase 9 siRNA vector試劑盒及其他產(chǎn)品載體

Abcam  ab12505Negative control siRNA vector （pGB control）20ug4518Negative control siRNA vector （pGB control）試劑盒及其他產(chǎn)品載體

Abcam  ab12506siRNA cloning vector （pGB）20ug3996siRNA cloning vector （pGB）試劑盒及其他產(chǎn)品載體

Abcam  ab1251Mouse monoclonal [FR4D11/F3] to CD10500ul3996CD10hystemcell一抗

Abcam  ab1252Mouse monoclonal [BRA4F1] to CD15500ul3996CD15hystemcell一抗

Abcam  ab12524Rabbit polyclonal to GPCR GPR1850ug3996GPCR GPR18hystemcell一抗

Abcam  ab12525Rabbit polyclonal to GPCR GPR3550ug4607GPCR GPR35hystemcell一抗

Abcam  ab12528Rabbit polyclonal to GPR 15250ug4607GPR 152hystemcell一抗

Abcam  ab1253Goat polyclonal to Myc tag （Agarose）100ug3996Myc taghystemcell一抗

Abcam  ab12531Rabbit polyclonal to GPCR G2A50ug4607GPCR G2Ahystemcell一抗

Abcam  ab12534Rabbit polyclonal to GPCR15050ug4607GPCR150hystemcell一抗

Abcam  ab1254Mouse monoclonal [CB16] to CD16500ul3996CD16hystemcell一抗

Abcam  ab12541Rabbit polyclonal to GPCR GPR12050ug3996GPCR GPR120hystemcell一抗

Abcam  ab12542Rabbit polyclonal to GPCR GPR14650ug3996GPCR GPR146hystemcell一抗

Abcam  ab12543Rabbit polyclonal to GPCR GPR1550ug3996GPCR GPR15hystemcell一抗

Abcam  ab12547Rabbit polyclonal to PTPN20200ul3996PTPN2hystemcell一抗

Abcam  ab12548Rabbit polyclonal to GPR2/CCR1050ug3996GPCR GPR2/CCR10hystemcell一抗

Abcam  ab1255Mouse monoclonal [CB19] to CD19500ul3996CD19hystemcell一抗

Abcam  ab12550Rabbit polyclonal to PTPD1200ul3996PTPD1hystemcell一抗

Abcam  ab12551Rabbit polyclonal to GPCR GPR2050ug3996GPCR GPR20hystemcell一抗

Abcam  ab12552Rabbit polyclonal to PTPD2100ug3996PTPD2hystemcell一抗

Abcam  ab12553Rabbit polyclonal to HDPTP200ul3996HDPTPhystemcell一抗

Abcam  ab12554Rabbit polyclonal to PTP zeta/ Phosphacan200ul2664PTP zeta/ Phosphacanhystemcell一抗

Abcam  ab11414Mouse monoclonal [SN6] to CD105100ug3996CD105hystemcell一抗

Abcam  ab11415Mouse monoclonal [SN6] to CD105 （FITC）100ug5029CD105hystemcell一抗

Abcam  ab11417Mouse monoclonal [D9D10] to Interferon gamma （FITC）50ug3996IFN-gammahystemcell一抗

Abcam  ab11418Mouse monoclonal [Z-ZE4] to IGFBP150ug3996IGFBP1hystemcell一抗

Abcam  ab11419Mouse monoclonal [9C8] to GADD15350ug4418GADD153hystemcell一抗

Abcam  ab1142Rabbit polyclonal to Bcl10100ul3996Bcl-1hystemcell一抗

Abcam  ab11420Rabbit polyclonal to ERp2950ul3996ERp29hystemcell一抗

Abcam  ab11421Rabbit polyclonal to ERp5750ul3996ERp57hystemcell一抗

Abcam  ab11422Rabbit polyclonal to ERp7250ug3996ERp72hystemcell一抗

Abcam  ab11423Mouse monoclonal [1234] to Rapsyn50ug3996Rapsynhystemcell一抗

Abcam  ab11424Rabbit polyclonal to EDG150ug3996EDG1hystemcell一抗

Abcam  ab11425Mouse monoclonal [1351] to Syntrophin50ug3996Syntrophinhystemcell一抗

Abcam  ab11426Rabbit polyclonal to Calbindin - Neuronal Marker50ug3996Calbindinhystemcell一抗

Abcam  ab11427Rabbit polyclonal to Parvalbumin50ug3996Parvalbuminhystemcell一抗

Abcam  ab11428Rabbit polyclonal to S100 alpha50ug3996S100 alphahystemcell一抗

Abcam  ab11429Rabbit polyclonal to RELM beta50ul3996RELM betahystemcell一抗

Abcam  ab1143Rabbit polyclonal to Acinus100ul3996Acinushystemcell一抗

Abcam  ab11430Rabbit polyclonal to Resistin50ul3996Resistinhystemcell一抗

Abcam  ab11431Rabbit polyclonal to Resistin50ug3996Resistinhystemcell一抗

Abcam  ab11432Rabbit polyclonal to PDIA650ul3996P5hystemcell一抗

Abcam  ab11433Mouse monoclonal [5] to VCP50ul4418VCPhystemcell一抗

Abcam  ab11434Rabbit polyclonal to Ataxin 750ug3996Ataxin 7hystemcell一抗

Abcam  ab11436Rabbit polyclonal to PSMD750ug3996Proteasome 19S S12hystemcell一抗

Abcam  ab11437Rabbit polyclonal to Proteasome 20S alpha 550ug3996Proteasome 20S alpha 5hystemcell一抗

Abcam  ab11438Mouse monoclonal [LZA2] to Listeria monocytogenes250ug3996Listeria monocytogeneshystemcell一抗

Abcam  ab11439Mouse monoclonal [LZH1] to Listeria monocytogenes250ug3996Listeria monocytogeneshystemcell一抗

Abcam  ab1144Rabbit polyclonal to Acinus100ul3996Acinushystemcell一抗

Abcam  ab11441Mouse monoclonal [LX32] to Listeria monocytogenes250ug3996Listeria monocytogeneshystemcell一抗

Abcam  ab11442Mouse monoclonal [HBe7] to Hepatitis B Virus E Antigen250ug3996HBeAghystemcell一抗

Abcam  ab11443Mouse monoclonal [HBe3] to Hepatitis B Virus E Antigen （HRP）200ug3996HBeAghystemcell一抗

Abcam  ab11444Mouse monoclonal [HBe8 ] to Hepatitis B Virus E Antigen500ug3996HBeAghystemcell一抗

Abcam  ab11447Mouse monoclonal [B-G5 ] to IL2 （FITC）50ug3996IL-2hystemcell一抗

Abcam  ab11448Rat monoclonal [MQ1-17H12] to IL2250ug3996IL-2hystemcell一抗

Abcam  ab11449Mouse monoclonal [B-E8 ] to IL6100ug3996IL-6hystemcell一抗

Abcam  ab1145Rabbit polyclonal to FLASH100ul3996FLASHhystemcell一抗

Abcam  ab11450Mouse monoclonal [B-K8 ] to IL8100ug3996IL-8hystemcell一抗

Abcam  ab11451Mouse monoclonal [4D5] to IP10250ug3996IP-10hystemcell一抗

Abcam  ab11453Mouse monoclonal [h.mcp.3] to MCP3250ug3996MCP-3hystemcell一抗

Abcam  ab11456Mouse monoclonal [1E8-269] to TGF alpha1ml3996TGF alphahystemcell一抗

Abcam  ab11457Mouse monoclonal [B-D9] to TNF alpha （FITC）50ug3996TNF-alphahystemcell一抗

Abcam  ab12555Rabbit polyclonal to PTP gamma100ug3996PTP gammahystemcell一抗

Abcam  ab12556Rabbit polyclonal to SAP1200ul3996SAP1hystemcell一抗

Abcam  ab12557Rabbit polyclonal to GLEPP1100ug3996GLEPP1hystemcell一抗

Abcam  ab12558Rabbit polyclonal to GPCR GPR2650ug4940GPCR GPR26hystemcell一抗

Abcam  ab12559Rabbit polyclonal to GPCR GPR2750ug3996GPCR GPR27hystemcell一抗

Abcam  ab12560PTPD1 peptide100ug2010PTPD1蛋白/多肽多肽

Abcamab1133Rabbit polyclonal to GABARAP100ul3996GABARAP抗體一抗

更多詳情，請(qǐng)：     

重慶市華雅干細(xì)胞技術(shù)有限公司